Ooh... That's a good question... (IF aliens were to be real. That's up for debate...
I mean, when you look at it, the biggest chances are that they're either or really similair to something we know on earth, or they're something soo diffirent that we possibly won't even percieve them as living creatures.
(@Creationists. For you, aliens don't exist, evolution didn't happen. I understand, I'm just talking about the possibilities if it were. c; )
Life on Earth has come a long way. It started out with a mere bunch of single-celled organisms with little to no defense or knowledge of what was going on, but after these billions of years of this process-of-elimination game, that is evolution, a lot of us have turned into things that know very well what they're doing, or even what they're loving.
You could argue that alien life could look very similair to what we've seen in the movies, or even to human / life on earth itself, as the way we've evolved may just be a path towards the optimum form of life.
And aliens on a diffirent planet, that started with the same enviremental condition that us "Terrestial" scientists deem so quintessential, (water, oxygen, the right temprature, no radiation, etc.) they may very well follow almost exactly the same path of evolution, and end up looking just like us "Earthlings" if not for some extra, or missing apendages, or odd shapes.
But, on the opposite side, you could also argue that the chances of these requirements being met, somewhere in the universe, are much, much smaller than life just starting with, to us, unoptimal condition, leading life to look soo diffirent than to what's on Earth, that we can't even comprehend it.
There may be a planet, somewhere out there, where life is based on liquid metal, instead of water, like we humans are. These aliens may not have eyes, or ears, but they may navigate and/or communicate via magnetic fields. And, instead of brains with neurons, and a nervous system, they have actual vains of copper as nerves, and a brain that's constructed of almost the very same materials as our computers!
There may be a planet, where life isn't mobile at all. Where plants and funghi are instead sentient, just like humans are, and communicate with each other via a network of intergrown roots. Something that we wouldn't see as "alive" and would harvest, or destroy, without thinking about it, whilst we are actually commiting genocide.
We don't know... :I
But, I think it's either similair, or just completely, mindboggelingly diffirent.
If you could become an immortal ghost, that is free to spectate what happends in the world, for the rest of time, whilst being incapable of interacting with anything. Would you accept?