Like Zombiezu, I have a goal to make these topics a reality, although my side is much more artificial...
If the technological projection of the Deus Ex Universe is correct, there will be widespread Mechanical Augmentation by at least 2027. Only another fifteen years from now. That would mean, if you had the money, you could pretty much become your persona. Some would be more complex than others... a lot of you would need replacement of bone and muscle, and artificial fur impanted into your mechanical shell. I'm not sure about the skull, however... In Deus Ex: Human Revolution, there are many people who have full-body Augmentations, all save for their heads. Lawrence Barrett looks to have a jaw replacement, most probably have enhanced or mechanical eyes, and Adam Jensen can aquire many brain Implants and Augmentations, but that's about it for cranial Augmentations. That is probably a high-risk or even a no-go area if you intended to change the shape of the skull, as they would have to remove your brain and build you a new skull that is still 'roomy' enough to house it. Some day it will work. Some day.
Special characteristics of mine might still be out of reach for many years after such advancements, due to the fact that he can take small quantities of non-organic matter, like plastic and metal, and quickly use them to repair of modify his own structure, or simply change the shape of the object without combining it with himself. He could turn a small PVC pipe into a knife, for example, without having to cut and shape it by hand. The highly advanced upgrades given to him by the Subjugators would certainly be impossible for a VERY long time, which are the actual shapeshifting abilities he usually exhibits in role-plays, along with the technology to store materials in a bank of sorts and 'download' them to use whenever he needed more mass than he had on his body, and then store them later when changing to a less massive form.