Favorite Weapons huh? Also nice one Kio!!
Assassin's Creed's hidden blades appears to be everyone's favorite, cause lets face it... those things look and are badass, I love what they did with them in A.C.3 having them flip into daggers!!! epic!
I like Devil May Cry 4 Nero's sword The Red Queen, looks beautiful and is wicked too!
And I'm certain a lot of you have never really heard of this game, Asura's Wrath, weapon would have to be well, His whole freaking body, he is just anger given a body and even without his arms will stomp the hell out of you or bash his own head against you... Not sure this counts but he is just awesome!
As for gun wise... well not much of choice other than Halo's Needler gun... or pink death bringer!!! lol!