Fortunately, and sadly, there's not many people I love. Plenty that I like, not really many at all that I love. So, sacrificing my mother and two of my closest friends to save the world, while painful, I would do for the greater good. But I would make sure they knew beforehand what was going on, why, and give them the option to voluntarily be the sacrifices.
If you were taken through a portal to an alternate or another world where that world is dying and the anthro inhabitants seek entry into your world, you would return with them as a liaison but one human would have to be pulled from your world and left on their dying world for every individual one as a price of the spell, would you do it?